yes, and this is the detailed steps of how to use gateway 3ds card. http://r4i-3ds.com/nds-r4-3ds/how-to-use-gateway-3ds-flashcard-to-work-on-3ds-v4-5-0-264/
Found this guide on how to setup gateway 3ds : http://www.modchipfactory.com/blog/...teway-3ds-to-play-3ds-games-on-n3ds-v4-1-4-5/ ,it seems the setup steps is complex than normal flashcart.