In some cases yes. I did this with World Of Warcraft as follows: I put each disc in starting with disc 4 and copied all data to one directory on my hard drive, overwriting previous data each time. So you would do disc 4, disc 3, disc 2, disc 1. At the end you'll have the data files from all 4 discs with the autorun and installer from the first disc, and the installation automaticly detected the data and never asked for another disc. This sometimes works and sometimes doesn't depending on the protection of the discs. -EDIT- Also depends on how the installer itself is set up.
