When I try to save the game it the Acekard 2i says the save file is corrupt and will be deleated. This only occurs on MySims Agent. Any ideas?
Did you DLDI patch the game? If not do it. If it still as issues then I'd first delete the current save file, if that doesn't fix it then get a different copy of the game and delete the old one.
I'm having the same problem and it does it with mysims kingdom too, they both worked fine on my m3real and r4i, it's only the acekard 2i they mess up on. I think they're working on a fix for it though as in the firmware updates they had the same problem with the original my sims and have fixed that, so fingers crossed.