The method I use is DVD Decryptor (note this program is free and available on this site)to create the iso image and burn with whatever burning program is handy. Depending on burner compatibility you could Write and burn the iso both directly from DVD Decryptor.
to burn it in Nero you would open Nero burning rom then close the new complation window then from the top menu's select recorder,burn image a new window opens from the file types drop down menu select image files (*.nrg,*.iso,*.cue)browse to were the image file is stored click it then click open,a new window will open on here select your burn speed make sure finalise dvd is ticked then click burn you should not have to alter any other setting hope this helps
Is the best way to backup a ps2 game to read/write with dvd decrypter or should i create an image with dvd decrypter and burn with nero or alcohol? Does it really matter and is the best write speed 1x instead of something like 4x?