How to preserve the activation of a program?

My computer has a yet-undiagnosed software or hardware problem that has required me to reformat and reinstall all software several times. I purchaed a copy of DVD XCopy Xpress a while back, and, while 321 Studios had kindly given me several more activations, these are of little value now. What I would like to know is how I can either back up that single program (probably unlikely) or just the files and registry keys that contain the activation for my copy of the program. Or, perhaps there is another way to provide the activation.

I hesitate to rely on a full system backup until I locate the source of my frequent crashes lest I back up the problem along with everything else.

Thanks.